Beside being the vector for dengue fever, Aedes aegypti also disturbs human "life since the female bites and absorbs blood particularly in the morning between 08. 00 - 12. 00 and in the afternoon between 15.00 -17.00
A lot of efforts have been made to solve dengue fever problems. These include chemical method, physical method and biological control. So far mosquito control still emphasizes chemical method, that is by using insecticide. Repeated use of insecticide causes a new problem, namely, it kills non target insect and vector resistance. The negative effect caused by chemical or insecticide encouraged scientists to find an alternative method, that is biological control. One of the methods that given priority to be developed as a controlling agent is entomophatogenic Metarhizium anisopliae fungus because it has destruxins that has been considered to be a new generation of insecticide substance.
This study aimed at finding out the toxicity of M. anisopliae to Aedes aegypti mosquito larvae by determining its Lethal Concentration (LC) at 50 and 90. In addition, it also aimed at finding out the number of M. anisopliae conidiosphore at the respective concentrations.
The result of the study shows that entomophatogen kills 50% (LC 50) larvae instar III Ae aegypti that comes from Denpasar at the 2.955 x I0' dilution level in 200 ml of water and 90% (LC 90) at the 8.861 x 10' dilution level in 200 ml of water in laboratory condition. There is a significant difference in the number of conidia and the entomophatogenic lethal power at each concentration.