KARAKTERISASI DAUN MIANA (Plectranthus scutellarioides (L.) Bth.) DAN BUAH SIRIH (Piper betle L.) SECARA FISIKO KIMIA DARI RAMUAN LOKAL ANTIMALARIA DAERAH SULAWESI UTARA

Lisdawati, Vivi and Mutiatikum, Daroham and Alegantina, Sukmayati and Astuti N, Yun (2008) KARAKTERISASI DAUN MIANA (Plectranthus scutellarioides (L.) Bth.) DAN BUAH SIRIH (Piper betle L.) SECARA FISIKO KIMIA DARI RAMUAN LOKAL ANTIMALARIA DAERAH SULAWESI UTARA. Media Penelitian dan Pengembangan Kesehatan, 18 (4). pp. 213-225. ISSN 0853-9987

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Abstract

Multidrug-resistant Plasmodium falciparum strains are an increasing problem in endemic areas and are partly responsible for the worsening malaria situation around the world. New cheap and effective compounds active in combination with available drug in the field, such as indegenous traditional medicine, are urgently needed. The aim of this work was to characterize the simplitia and extracts of an indegenous traditional medicine which usually used in North Sulawesi. Since this indigenous traditional medicine has been largely used and well-tolerated in humans, secondary metabolites derivatives of the plants could be in the near future associated with already available drugs. In order to delay the spread of P. falciparum resistance. Non polar, semi polar and polar extracts of P. scutellarioides folium and P. betle fruit are prepared of each plants part obtained, then evaluated by using chromatography and densitometry methods following identification.

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