Seroepidemiologi Infeksi Virus Morbilli pada Anak Balita di Jawa Tengah dalam Rangka Imunisasi terhadap Morbilli

A sero immunity survey on measles virus infection among children under 5 years of age in Central Java Province was conducted in three types of areas, namely: rural, urban and measles-virus endemic areas. The objective of the study is to obtain the basic data of immune status from children under 5 years of age in connection with mass vaccination program againts measles virus infection in Indonesia. A total of 763 peripheral blood samples were collected in filter paper disc from children under 5 years of age divided into age structure. Antibodies titers in blood were measured by haemagglutination inhibition test against measles antigen. The result showed that children of 7-9 months of age were highest in the endemic areas (17,6%), high in urban (7,7%) and none of the 13 children examined in the rural was infected. The maternal antibodies in infants of 0-6 months of age were highest in the endemic areas (35.3%) as compared to 4.3% and 10% in the urban and rural areas. In children of more than 10-11 months old, the antibodies againts measles virus were highest in the urban (31%), high in endemic areas (23%) and low in rural (6.9%), whereas among the 2-5 years age-group, the antibodies level was about equal in both the urban and endemic areas, but lower in the rural areas.