Pengobatan Malaria vivax dengan Pemberian Klorokuin dan Primakuin Secara Harian dan Paket di Jawa Tengah

Ompusunggu, Sahat (1994) Pengobatan Malaria vivax dengan Pemberian Klorokuin dan Primakuin Secara Harian dan Paket di Jawa Tengah.

Abstract

Due to the limitation of manpower in the Health Centres, packet (bulk) of drug distribution procedure is now being used to replace the daily supervised drug administation, procedure for vivax malaria treatment programme in the field. To evaluate the efficacy of both procedure (daily and packet) this study was performed in Central Java in 1989-1990. The study subjects were vivax malaria patients, from all age groups, which were devided into two groups. Group I received the drug daily (standart treatment ) and group II throught packet procedure. The dose for chloroquine was 25 mg/kg BW in 3 days and for primaquine was 5 mg per day for 5 days. Blood examinations were performed on day 2,7 and 28 followed by monthly examinations until 6 months after the treatment was started. The result showed that treatment failure was relatively high in both groups: 29,27 % from 41 patients who received daily treatment and 35,01 % from 91 patients with packet procedure. Cure rate in the daily treatment groups was 65,62 % and 62.29 % from the packet procedure groups. It is concluded that packet administration of vivax malaria drug is as effective as daily supervised administration. Combination of chloroquine and primaquine was succesful for treatment of vivax malaria in 95,55 % in daily groups and 86,89% in packet groups although the drug dosage is not yet optimal.

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