Antitoksin Difteri pada Bayi setelah di Imunisasi dengan Vaksin DPT dan DT

Prijanto, Muljati and Suprijanto, Eko and Siburian, Farida and Kameyama, Shoichi (1982) Antitoksin Difteri pada Bayi setelah di Imunisasi dengan Vaksin DPT dan DT. Project Report. Perpustakaan Badan Penelitian dan Pengembangan Kesehatan.

Abstract

A field trial on DPT vaccine was carried out in Kecamatan Mojoagung and Sumobito, Kabupaten Jombang, East Java. Samples of 1100 infants aged between 3-8 months were selected randomly from this area. The samples were decided into three groups; group I of 234 infants received DPT-DPT-DT vaccine, group II of 242 infants received DT-DT-DPT vaccine and group III received DPT-DT-DPT vaccine. Injection was 0.5 ml and given deep subcutaneous. The potency and cold chain of the vaccine was tested and fulfilled the requirement: A passive hemagglutination test was used to determine the antitoxin. The immune status against diphtheria in each group was observed before and after immunization. The results were 8.5 - 62.15 % of group I, 10.3 - 64.05 % of group II and 14.2 - 60.93 % of group III respectively. The mean titer of diphtheria antitoxin after immunization in each group was between 0.02 - 0.03 HAU per ml.

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