Nilai Diagnostik Indeks Wayne dan Indeks Newcastle untuk penampisan kasus hipertiroid

Kusrini, Ina and Kumorowulan, Suryati (2010) Nilai Diagnostik Indeks Wayne dan Indeks Newcastle untuk penampisan kasus hipertiroid. Buletin Penelitian Kesehatan, 38. ISSN 0125-9695

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Abstract

Hyperthyroidism is a state of thyrotoxicosis as a result of thyroid production, while true diagnosis is done by biochemical testing. This study was observational research with a cross sectional design study. Respondents in this study were women who 20-60 years old who had enlarge thyroid gland. Location for this study in non-endemic areas with median of UIE is over 300ug/l. The number of samples in this research is 36 people. Data were analyzed using sensitivity. In this study a result that at Wayne index value of the area under the curve (AUC) 0,741. P. value=0,0085 (p<0,05) with a sensitivity of 0,55 and specificity of 0,925. While at Newcastle index value of Area Under the Curve (AUC) 0,66 p value= 0,0543 (p. 0,05), which means there is no difference in AUC with a specificity value of 0,33, 05 and a specificity of 0,096. In the study showed the correction value Cut-off point Wayne index . 21 had the highest sensitivity o,05 and specificity 1. And obtained correction value index Cut-point for New Castle> 31 had the highest sensitivity o,77 and specificity is 0,66.

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