Efektivitas Vaksinasi Toksoid Serap Tetanus pada Ibu-ibu Hamil dan Bayi yang Dilahirkannya di Yogyakarta

Prijanto, Muljati and Suprijanto, Eko and Isbagio, Dyah Widyaningroem and Haryanto, Haryanto (1985) Efektivitas Vaksinasi Toksoid Serap Tetanus pada Ibu-ibu Hamil dan Bayi yang Dilahirkannya di Yogyakarta.

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Abstract

A Study was carried out in 6 subdistricts in Yogyakarta. A total of 56 and 163 blood samples were collected from 4-7 months pregnant women and mothers 17-35 years of age. The objectives of this study was to know the immune respos against tetanus after being vaccinated with tetanus toxoid adsorbed during pregnancy (a prospective study) and know the decrease of the antibody level 1-4 years after vaccination (a retrospective study) Tetanus antitoxin titration was performed by pasive haemaglutination (PHA) test. Tetanus toxoid absorbed used in this study was produced by Biofarma, Bandung. Two immunization doses againts tetanus with 1-2 months interval gives 100% protection to the babies at birth, and at the age of 3 month the babies still have protective titres againts tetanus. The pecentage of mothers with tetanus protective titres decreased from 80.70 % to 53.57 % with the mean antibody titres decreased from 0.415 HAU/ ml to 0.066 HAU/ml after 1-4 years vaccination

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