Gambaran Perkembangan Antibodi terhadap Komponen Protein Cacing Mikrofilaria malayi dari Transmigran di Sulawesi Tenggara

Utami, Basundari Sri and Kurniawan, Liliana and Widjaja, Robert and Harum, Syahrial (1989) Gambaran Perkembangan Antibodi terhadap Komponen Protein Cacing Mikrofilaria malayi dari Transmigran di Sulawesi Tenggara. Buletin Penelitian Kesehatan, 17 (3). ISSN 0125-9695

Preview

Text 470-1584-1-PB.pdf - Published Version Download (317kB) | Preview

Abstract

The immune response to microfilarial antigen in malayi filariasis was found more prominent in amicrofilaremic individuals than in the microfilaremics. It has been shown that in microfilaremic individuals antibody plays a role in reducing microfilaremics. The targets antigens of antibody (IgG) were shown to be protein components of microfilariae with moleculer weight of 75, 70 and 25 Kd. This prospective study was aimed at detecting IgG against microfilariae in transmigrans, who had settled into an filarial endemic area. Sera of 10 individuals at 8,13,26,39 and 52 months after settling, were examined by ELISA and western Blott againts microfilariae of B. malayi. Four out of 10 transmigrants showed IgG recognized the protein components of 77,70 and 31 Kd and were shown at 39,52 and 8 months after settling respectively, the IgG against components of 77 and 70 Kd were revealed later than the one against 31 Kd.

Actions (login required)

View Item